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Nanobiotechnology
Údaje o názvu Nanobiotechnology [elektronický zdroj] : inorganic nanoparticles vs organic nanoparticles / edited by Jesus M. de la Fuente and V. Grazu Vyd.údaje [S.l.] : Elsevier, 2012. Fyz.popis 1 online zdroj (xix, 520 s. : il.) ISBN 9780124157699 (electronic bk.) 0124157696 (electronic bk.) 9780123983046 (electronic bk.) 0123983045 (electronic bk.) Edice Frontiers of nanoscience ; v. 4 Poznámky o skryté bibliografii a rejstřících Obsahuje bibliografické odkazy a rejstřík Úplný obsah Machine generated contents note: pt. I Synthesis and Characterization of Nanoparticles -- 1.Synthesis Applications of Gold Nanoparticles / Pablo del Pino -- 1.Introduction -- 2.Ancient Uses of GNPs -- 3.Synthesis of GNPs -- 4.Common Anisotropic GNPs for Bioapplications -- 4.1.Nanorods -- 4.2.Nanoplates -- 4.3.Gold Nanoshells -- 4.4.Nanocages and Hollow Nanostructures -- 4.5.Branched Nanostructures, Nanostars, or Nanoflowers -- 5.Derivatization of GNPs -- 6.Bioapplications of GNPs -- References -- 2.Synthesis of Inorganic Nanoparticles / Maria del Puerto Morales -- 1.General Strategies for the Synthesis of Uniform Inorganic Nanoparticles -- 1.1.Mechanism of Nanoparticle Formation -- 1.2.Strategies for Size and Shape Control -- 1.3.Synthesis Methods -- 2.Magnetic Nanoparticles -- 2.1.Precipitation of Salts in Aqueous Medium -- 2.2.Hydrothermal -- 2.3.Microemulsions -- 2.4.Polyol Process -- 2.5.Decomposition in Organic Media -- 2.6.Aerosol Pyrolysis -- 2.7.Others: Anisometric Particles -- 3.Hybrids -- 3.1.Inorganic-Inorganic -- 3.2.Organic-Inorganic -- 3.3.Multicomponents -- 4.Concluding Remarks -- References -- 3.Synthesis of Inorganic Nanocrystals for Biological Fluorescence Imaging / Peter Reiss -- 1.Introduction -- 1.1.Semiconductor Nanocrystals as Fluorescent Biological Labels -- 1.2.Basic Properties of Semiconductor Nanocrystals -- 1.3.Nanocrystal Synthesis -- 2.Aqueous Synthesis of Nanocrystals -- 2.1.CdTe Nanocrystals -- 2.2.ZnSe Nanocrystals -- 3.Synthesis in Organic Medium -- 3.1.Cadmium Chalcogenide Nanocrystals -- 3.2.Doped II-VI Semiconductor QDs -- 3.3.III-V Semiconductor Nanocrystals -- 3.4.Nanocrystals of Ternary Chalcopyrite Semiconductors -- 3.5.Cd3P2 and Cd3As2 Nanocrystals -- 3.6.Aqueous Phase Transfer of Nanocrystals Prepared in Organics -- 4.Conclusions -- References -- 4.Synthesis of Organic Nanoparticles / Sergio E. Moya -- 1.Introduction -- 1.1.Organic Versus Inorganic -- 2."Top-Down" Techniques -- 3."Bottom-Up" Techniques -- 3.1.Micelles, Vesicles, and Liposomes -- 3.2.Polymer Micelles, Polymersomes, and Polymer Conjugates -- 3.3.Dendrimers -- 3.4.Nanocapsules -- 3.5.Polymeric NPs -- References -- 5.Synthetic Strategies to Create Dendrimers: Advantages and Drawbacks / Javier Rojo -- 1.Introduction -- 2.Divergent Synthetic Approaches -- 3.Convergent Synthetic Approaches -- 4.Conclusions -- References -- pt. II Biotechnological Applications -- 6.Applications of Inorganic Nanoparticles for Biotechnology / Catherine C. Berry -- 1.Magnetic Nanoparticles -- 1.1.Magnetic Resonance Imaging -- 1.2.Hyperthermia -- 1.3.Magnetic Targeted Therapies/Delivery -- 2.Gold Nanoparticles -- 2.1.Biological Imaging -- 2.2.Cell Delivery Vehicles -- 2.3.Biosensors -- 3.Quantum Dots -- 3.1.Biological Imaging -- 3.2.Targeted Therapies -- 4.Carbon Nanotubes -- 4.1.Neuronal Tissue Engineering -- 4.2.Imaging and Cancer Treatment -- References -- 7.Investigating Nanoparticle Internalization Patterns by Quantitative Correlation Analysis of Microscopy Imaging Data / Pilar Rivera Gil -- 1.Introduction -- 2.Time-Resolved Quantitative Correlation Analysis -- 2.1.Image Acquisition -- 2.2.Quantitative Analysis of Colocalization -- 3.Example Study: Internalization Pathways of Superparamagnetic Iron Oxide NPs -- 3.1.Preparation and Characterization of SPIONs -- 3.2.Results -- 4.Limitations and Conclusion -- References -- 8.Organic Nanoparticles / Isabel Segura Gil -- 1.Introduction -- 2.Use of Nanoparticles in Nucleic Acid Delivery -- 2.1.Background -- 2.2.Engineered Biomaterials for Vector Backbones -- 2.3.Environmental Interactions -- 2.4.Intracellular Trafficking -- 3.Immunoassays -- 3.1.Background -- 3.2.Nanotechnology and Improvement of Sensitivity -- 4.Nanoparticles and the Fundamental Study of Cell Adhesion Mechanisms -- 4.1.Adhesion Basics -- 4.2.Liposomes as Biomimetic Cell Membranes -- 4.3.Polymeric Beads -- 5.Conclusion -- Acknowledgments -- References -- pt. III Applications in Diagnostics and Biosensing -- 9.Application of Inorganic Nanoparticles for Diagnosis Based on MRI / Maria L. Garcia-Martin -- 1.Introduction -- 2.Magnetic NPs for MRI -- 2.1.The Superparamagnetism Phenomenon -- 2.2.Conventional Iron-Oxide-Based NPs for MRI -- 2.3.Magnetic NPs in the Nanotechnology Era -- 3.MRI Methods to Image NPs -- 3.1.Susceptibility-Weighted Imaging -- 3.2.Positive Contrast Techniques -- 3.3.Quantitative Susceptibility Mapping -- 3.4.Ultra-Short TE and Zero TE MRI -- References -- 10.Biosensors Based on Nanoparticles and Electrochemical Detection / Pilar Batalla -- 1.Introduction -- 2.Electrochemical Sensors -- 2.1.GNPs Mixed with the Electrode Material -- 2.2.Direct Deposition of GNPs onto the Electrode -- 2.3.GNPs Immobilized onto Self-assembled Monolayers -- 2.4.GNPs as a Label -- 2.5.GNPs and Carbon Nanotubes -- 3.Optical Sensors -- 3.1.Surface Plasmon -- 3.2.SPR and Localized SPR -- 3.3.Scanometric Detection of Light Scattering -- 3.4.Surface-Enhanced Raman Scattering -- 3.5.Fluorescence Quenching -- 3.6.Lateral LFIAs -- 4.Mass-Sensitive Sensors -- References -- 11.Magnetic Nanoparticles for Application in Biomedical Sensing / Lee Josephson -- 1.Introduction -- 2.Magnetic Relaxation Properties -- 3.Magnetic Relaxation Switches -- 3.1.Mechanism of MRSws -- 3.2.Type I MRSw -- 3.3.Type II MRSw -- 3.4.Aggregation-Based Implantable MR Devices -- 3.5.Post Filtration MR Sensors -- 4.Applications of MRSw -- 4.1.Detection of Proteins -- 4.2.Detection of Enzyme Activities -- 4.3.Detection of Small Molecules -- 4.4.Detection of Nucleic Acids -- 4.5.Detection of Viruses -- 4.6.Detection of Cancer Cells -- 4.7.Detection of Bacteria -- 5.Other Types of MP-Based Sensors -- 5.1.Magnetoresistive Sensors -- 5.2.Spin Valve Sensors -- 5.3.Magnetophoretic Sensors -- 6.Conclusions -- References -- 12.Quantum Dot Nanoparticles for In Vitro Sensing / Niko Hildebrandt -- 1.Introduction -- 2.Targets of Biosensor -- 3.Biosensor Requirements -- 4.Functionalization of NPs -- 5.Recent Applications -- 5.1.QDs and AuNPs -- 5.2.QDs in Charge Transfer -- 5.3.QD as CRET Acceptors -- 5.4.QDs as FRET Acceptors -- 6.Conclusion -- Acknowledgement -- References -- pt. IV Nanoparticles for Therapy -- 13.Hyperthermia Using Inorganic Nanoparticles / Beatriz Pelaz -- 1.Introduction -- 2.Hyperthermia Based on SPM-NPs: Magnetic Fluid Hyperthermia -- 3.Hyperthermia Based on Gold Anisotropic NPs: Photothermal Therapy -- References -- 14.Nanocarriers as Nanomedicines: Design Concepts and Recent Advances / Christian Sanchez-Espinel -- 1.Introduction -- 2.Nanocarriers Fate: Barriers to Overcome -- 2.1.Absorption and Administration Route Implications -- 2.2.Biodistribution -- 2.3.Metabolism and Excretion -- 3.Targeting Strategies -- 3.1.Passive Targeting -- 3.2.Active Targeting -- 4.Triggered Release of the Therapeutic Agent -- 4.1.Temperature -- 4.2.pH -- 4.3.Ultrasounds -- 4.4.Redox -- 4.5.Enzymes -- 4.6.Temporal Control -- 5.Examples of Nanosystems for Drug Delivery -- 5.1.Inorganic Nanoparticles -- 5.2.Organic Nanosystems -- 5.3.Carbon Nanotubes -- 5.4.Hybrid Nanocarriers -- 6.Translation from Basic Research to the Healthcare Market -- 7.Scope -- References -- pt. V Toxicity and Regulation -- 15.Nanotoxicology / Amparo Casal -- 1.Introduction -- 2.Toxicology -- 3.Regulation -- 4.Toxicity of Biodegradable Nanostructures -- 4.1.Lipid-Based Nanostructures: Liposomes and Solid Lipid Nanoparticles -- 4.2.Dendrimers -- 4.3.Polymeric Ns -- 4.4.Albumin-Based Ns -- 4.5.Excipients and Emulsifiers -- 5.Toxicity of Non-biodegradable Nanostructures -- 5.1.Toxicity of Heavy Metals and Trace Metals -- 5.2.Asbestosis and Silicosis -- 5.3.Toxicity of Carbon-Based Ns -- 5.4.Metallic Nanoparticles -- 6.Conclusion -- Acknowledgements -- References -- 16.Overview of Nanomedicines Regulation in the European Union / Ignasi Gispert -- 1.Introduction -- 2.Medicinal Products -- 3.Medical Devices -- 4.Biological Products -- 5.Borderline and Combined Products -- 6.The Precautionary Principle and the Incremental Approach Strategy -- 6.1.The Precautionary Principle -- 6.2.The Incremental Approach Strategy -- References. Dal.odpovědnost Fuente, Jesus M. de la
Grazu, V.Předmět.hesla nanotechnologie * nanobiotechnologie * Nanotechnology * Biotechnology Forma, žánr elektronické knihy * Electronic books Konspekt 62 - Technika všeobecně MDT 60-022.532 * 62-022.532 DOI 9786613721686 Země vyd. Bez místa Jazyk dok. angličtina URL http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=490341 Druh dok. ELEKTRONICKÉ ZDROJE 
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